COA Verified
MOTS-C research vial

AGELESS · Compound 05

MOTS-C

Mitochondrial-derived peptide

MOTS-C is a mitochondrial-derived peptide, encoded within the mitochondrial genome, studied for its role in metabolic regulation and cellular stress response.

Limited supply
€51 Vial · 10mg · per unit, excl. shipping
Every order includes ultra-fine injectable needles and alcohol swabs, the smallest gauge, highest-grade, ready to use.
UPS Standard · €193-5 days, all EU
UPS Express · €2924-48 hours across the EU

Tracked, cold-chain and discreetly packaged. Choose your speed at checkout.

CategoryAGELESS · Longevity
FormatVial
In The BoxNeedles + alcohol swabs
Dose10mg
DeliveryUPS Standard 3-5 days · UPS Express 24-48h
Purity Target>99%
1

Also: request a COA or a wholesale quote.

Third-party testedCOA per batchCold-chain EU shippingDiscreet packaging
ONE% Pen
Add the instrument ONE% Pen Reusable machined aluminium. Buy once, it works with any compound.
€49
ONE% Cartridges
Complete the kit ONE% Cartridges · 5-pack Sterile replacement cartridges for the ONE% Pen.
€39

Research Overview

MOTS-C belongs to a rare class of peptides encoded not in the cell’s nucleus but inside the mitochondrial genome itself. That origin makes it a genuinely different kind of research tool, a signal that emerges from the cell’s power plant and speaks back to the rest of the cell about its energy status.

Interest in MOTS-C sits at the intersection of metabolism and longevity. It has been studied as a regulator of metabolic homeostasis and as an ‘exercise-mimetic’ signal, giving researchers a window into how mitochondrial stress and adaptation influence whole-cell behaviour and ageing.

As a mitochondrially derived peptide, MOTS-C demands careful handling and verified identity to yield clean results. ONE% holds it to the same >99% purity target as the rest of the line and supplies it lyophilised, batch-referenced.

Mechanism In Brief

MOTS-C is a mitochondrial-derived peptide implicated in metabolic regulation and the cellular stress response, influencing energy-sensing pathways including AMPK-related signalling.

Areas Of Research Interest

  • Mitochondrial signalling, retrograde communication to the cell
  • Metabolic homeostasis, glucose and energy-balance models
  • Cellular ageing, stress response and senescence research
  • Exercise mimetics, adaptation signalling without exertion
  • AMPK pathway, energy-sensing cascade studies

Handling & Reconstitution

Every ONE% compound ships as a lyophilised powder for stability in transit. Reconstitute with bacteriostatic water to the concentration your protocol requires, store at 2–8°C protected from light, and use within your laboratory’s validated window. Each vial is batch-referenced to its Janoshik Certificate of Analysis, available on request.

Compound FamilyMitochondrial-derived peptide
FormLyophilised powder
PresentationSingle sealed vial
ReconstitutionBacteriostatic water
Storage2–8°C, protect from light

Important

For research and laboratory use only. MOTS-C is supplied strictly as premium-grade research material with a batch Certificate of Analysis. It is not a drug, supplement, food, or cosmetic, and is not intended for human or veterinary use, diagnosis, treatment, or the prevention of any condition. All statements describe published research directions only.

mots-c in a cinematic frame

The Proof

Proof,
In One Frame.

Third-party tested, every batch. Every Certificate of Analysis released with the vial, not on request.

Complete Your Kit

Accessories.

The instrument and the consumables that go with the range. Reusable pen, cartridges, and the essentials.

ONE% Pen
ONE% PenReusable device
€49
ONE% Starter Kit
ONE% Starter KitPen + Cartridges · save €9
€79
ONE% Cartridges
ONE% Cartridges5-pack
€39
Alcohol Prep Pads
Alcohol Prep Pads100 pads
€14
Insulin Syringes
Insulin Syringes100-pack
€24
ONE% Travel Pouch
ONE% Travel PouchZip case
€34

Good To Know

Common Questions.

It ships as a lyophilised (freeze-dried) powder. In the lab it's reconstituted with bacteriostatic water to the concentration your protocol requires. Kept sealed, cold and dark, it stays stable until you need it.

Sealed at 2–8°C, protected from light. As a lyophilised powder it's stable in transit; once reconstituted, follow your laboratory's validated window.

No, every compound ships as a lyophilised vial and is reconstituted in the lab. The ONE% Pen is a separate reusable instrument for laboratories that want repeatable, graduated delivery instead of drawing by syringe each time. Buy it once; it is not tied to any one compound.

Every vial carries a batch code. Enter it on our batch verification page to pull up that batch’s Certificate of Analysis, or ask us for the certificate before you order, we would rather you check than take our word for it.

It is the target every batch of MOTS-C is held to, measured by HPLC at Janoshik and reported on the COA as a percentage of the total peptide content. Identity is confirmed separately by mass spectrometry. A purity figure without a named method and a batch reference behind it is marketing, not data.

Education · Read Before You Buy

MOTS-C: The Peptide Written Inside Your Mitochondria

Most peptides are encoded in the nucleus. MOTS-C is not, and that changes everything about how it is studied.

Read the deep-dive

Continue

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