AGELESS · Compound 05
Mitochondrial-derived peptide
MOTS-C is a mitochondrial-derived peptide, encoded within the mitochondrial genome, studied for its role in metabolic regulation and cellular stress response.
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MOTS-C belongs to a rare class of peptides encoded not in the cell’s nucleus but inside the mitochondrial genome itself. That origin makes it a genuinely different kind of research tool, a signal that emerges from the cell’s power plant and speaks back to the rest of the cell about its energy status.
Interest in MOTS-C sits at the intersection of metabolism and longevity. It has been studied as a regulator of metabolic homeostasis and as an ‘exercise-mimetic’ signal, giving researchers a window into how mitochondrial stress and adaptation influence whole-cell behaviour and ageing.
As a mitochondrially derived peptide, MOTS-C demands careful handling and verified identity to yield clean results. ONE% holds it to the same >99% purity target as the rest of the line and supplies it lyophilised, batch-referenced.
Mechanism In Brief
MOTS-C is a mitochondrial-derived peptide implicated in metabolic regulation and the cellular stress response, influencing energy-sensing pathways including AMPK-related signalling.
Every ONE% compound ships as a lyophilised powder for stability in transit. Reconstitute with bacteriostatic water to the concentration your protocol requires, store at 2–8°C protected from light, and use within your laboratory’s validated window. Each vial is batch-referenced to its Janoshik Certificate of Analysis, available on request.
Important
For research and laboratory use only. MOTS-C is supplied strictly as premium-grade research material with a batch Certificate of Analysis. It is not a drug, supplement, food, or cosmetic, and is not intended for human or veterinary use, diagnosis, treatment, or the prevention of any condition. All statements describe published research directions only.

The Proof
Third-party tested, every batch. Every Certificate of Analysis released with the vial, not on request.
Complete Your Kit
The instrument and the consumables that go with the range. Reusable pen, cartridges, and the essentials.






Good To Know
It ships as a lyophilised (freeze-dried) powder. In the lab it's reconstituted with bacteriostatic water to the concentration your protocol requires. Kept sealed, cold and dark, it stays stable until you need it.
Sealed at 2–8°C, protected from light. As a lyophilised powder it's stable in transit; once reconstituted, follow your laboratory's validated window.
No, every compound ships as a lyophilised vial and is reconstituted in the lab. The ONE% Pen is a separate reusable instrument for laboratories that want repeatable, graduated delivery instead of drawing by syringe each time. Buy it once; it is not tied to any one compound.
Every vial carries a batch code. Enter it on our batch verification page to pull up that batch’s Certificate of Analysis, or ask us for the certificate before you order, we would rather you check than take our word for it.
It is the target every batch of MOTS-C is held to, measured by HPLC at Janoshik and reported on the COA as a percentage of the total peptide content. Identity is confirmed separately by mass spectrometry. A purity figure without a named method and a batch reference behind it is marketing, not data.
Education · Read Before You Buy
Most peptides are encoded in the nucleus. MOTS-C is not, and that changes everything about how it is studied.
Read the deep-dive →Continue
Talk To Us
Ask for a Certificate of Analysis, a specific batch, or anything else, send a note and we answer as fast as we test.
info@onepercentpeptides.com